Insect stings cause at least 50 known deaths each year. Most of us develop redness and swelling at the site of an insect bite. However, if you are allergic to stinging insect venom you are at a risk of anaphylaxis. Most serious reactions are caused by five types of insects: fire ants, honey bees, yellow jackets, wasps and hornets. An accurate diagnosis and treatment can decrease anxiety and bring peace of mind. Allergy immunotherapy is the only treatment known to modify and prevent disease progression, and can be life-saving for those affected. Immunotherapy has been shown to be 97% effective in preventing a life-threatening reaction to an insect sting.